UPDATE- RESOLVED 3-21-2018:
Adobe has resolved the issue with a new version of Digital Editions (v 184.108.40.206628). This version is available for download from:https://www.adobe.com/solutions/ebook/digital-editions/download.html
Please see below for details of the error as originally reported.
There is a widespread issue with the latest version of Adobe Digital Editions (v 220.127.116.11275), as of March 20, 2018. Users are getting the following error:
Adobe has acknowledged the problem and is working to resolve it. In the meantime, there is a workaround, which is to uninstall the latest version of ADE and reinstall an older version available from https://www.adobe.com/solutions/ebook/digital-editions/download.html
. The download version on this page has been updated to a previous version, v.18.104.22.168634. Updates are also being posted to the Adobe forum thread at https://forums.adobe.com/thread/2467374